abstract：:In mammals, neurogenesis continues during adulthood in restricted places of the nervous system, namely the subventricular zone, the dentate gyms and the olfactory epithelium. A dual role of the second messenger nitric oxide has been reported in such places, either promoting or inhibiting proliferation of neuronal prec...

journal_title：Biological research

authors： Sulz L,Bacigalupo J

更新日期：2006-01-01 00:00:00

abstract：:Despite the fact that the concept of sheet-flow in the pulmonary microcirculation of mammals was introduced more than three decades ago, the capillary circulatory model still prevails in the physiological literature. Since cardiac output is identical in the systemic and in pulmonary circulations, it is noteworthy that...

journal_title：Biological research

authors： Günther B,Morgado E,Cociña M

更新日期：2005-01-01 00:00:00

abstract：:This study examined the effects of estrogen supplementation on markers of neutrophil infiltration and damage in skeletal muscle of rats following ischemia. Male and female gonad-intact rats, with or without 14 days of estrogen supplementation were subjected to two hours of hind-limb ischemia and sacrificed at 24, 48 o...

journal_title：Biological research

authors： Tiidus PM,Deller M,Bombardier E,Gül M,Liu XL

更新日期：2005-01-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is secondary to loss-of-function mutations in the dystrophin gene. The causes underlying the progression of DMD, differential muscle involvement, and the discrepancies in phenotypes among species with the same genetic defect are not understood. The mdx mouse, an animal model with dyst...

journal_title：Biological research

authors： Fadic R

更新日期：2005-01-01 00:00:00

abstract：:Although there is extensive literature about the effects of stimulants on sustained attention tasks in attentional deficit/hyperactivity disorder (ADHD), little is known about the effect of these drugs on other attentional tasks involving different neural systems. In this study we measured the effect of stimulants on ...

journal_title：Biological research

authors： López J,López V,Rojas D,Carrasco X,Rothhammer P,García R,Rothhammer F,Aboitiz F

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to compare the effects of Mediterranean-type diet (MD), high-fat diet (HFD), and red wine supplementation on plasma concentration of emergent haemostatic cardiovascular risk factors (HCVRF) and on variables of primary haemostasis (bleeding time, plasma von Willebrand factor and platelet aggre...

journal_title：Biological research

authors： Mezzano D

更新日期：2004-01-01 00:00:00

abstract：:Caffeic acid, rosmarinic acid and oligomers of caffeic acid with multiple catechol groups are all constituents of Salvia officinalis. Their antioxidant potential was investigated with regard to their radical scavenging activity and the stability and structure of the intermediate radicals. Pulse-radiolytic studies reve...

journal_title：Biological research

authors： Bors W,Michel C,Stettmaier K,Lu Y,Foo LY

更新日期：2004-01-01 00:00:00

abstract：:The expression of the acetyl xylan esterase II (axeII) gene from Penicillium purpurogenum is repressed by glucose and induced by xylan, as well as to a small degree by xylose and xylitol. This gene is expressed at neutral pH, but not under alkaline or acidic conditions, in agreement with previous findings for other xy...

journal_title：Biological research

authors： Chávez R,Schachter K,Navarro C,Peirano A,Bull P,Eyzaguirre J

更新日期：2004-01-01 00:00:00

abstract：:Changes in the redox state of the intracellular ryanodine receptor/Ca2+ release channels of skeletal and cardiac muscle or brain cortex neurons affect their activity. In particular, agents that oxidize or alkylate free SH residues of the channel protein strongly enhance Ca(2+)-induced Ca2+ release, whereas reducing ag...

journal_title：Biological research

authors： Hidalgo C,Bull R,Behrens MI,Donoso P

更新日期：2004-01-01 00:00:00

abstract：:Control of smooth muscle is vital for health. The major route to contraction is a rise in intracellular [Ca2+], determined by the entry and efflux of Ca2+ and release and re-uptake into the sarcoplasmic reticulum (SR). We review these processes in myometrium, to better understand excitation-contraction coupling and de...

journal_title：Biological research

authors： Matthew A,Shmygol A,Wray S

更新日期：2004-01-01 00:00:00

abstract：:Calcium regulation of several transcription factors involves different calcium-dependent signaling cascades and engages cytoplasmic as well as nuclear calcium signals. The study of the specific sources of calcium signals involved in regulation of gene expression in skeletal muscle has been addressed only recently. In ...

journal_title：Biological research

authors： Carrasco MA,Jaimovich E,Kemmerling U,Hidalgo C

更新日期：2004-01-01 00:00:00

abstract：:Allium cepa L. meristems were used as a plant model to study the p53-independent control of S and G2 phases by checkpoint pathways, in eukaryotic cells. Checkpoint blocks were induced at early and mid S by hydroxyurea. After their spontaneous override, cells became accumulated in G2-prophase, giving rise later on to a...

journal_title：Biological research

authors： Pelayo HR,Pincheira J,Giménez-Abián JF,Clarke DJ,de la Torre C

更新日期：2003-01-01 00:00:00

abstract：:Treatment of tumor-bearing mice with LD12.5 values of iodoacetate; IAA (1.84 mg/100 g b.w.) and/or dimethylsulphoxide; DMSO (350 mg/100 g b.w.) significantly increased the cumulative mean survival time and percentage of survivors and reduced the mean tumor weight, compared to tumor-bearing controls, however, a more pr...

journal_title：Biological research

authors： Fahim FA,Esmat AY,Mady EA,Ibrahim EK

更新日期：2003-01-01 00:00:00

abstract：:The development of an effective hypersensitive response (HR) in any plant system relies, not only in their gene composition and expression, but also on an effective and rapid signal transduction system. Lemon seedlings induce the phenylpropanoid pathway, which results in the de novo biosynthesis of the phytoalexin sco...

journal_title：Biological research

authors： Ortega X,Polanco R,Castañeda P,Perez LM

更新日期：2002-01-01 00:00:00

abstract：:Breast cancer is the most common malignancy among women. Chilean studies reveal that this cancer presents the third highest mortality rate. A family history of breast cancer is one of the major risk factors for the development of this disease. BRCA1 and BRCA2 are the two main hereditary breast cancer susceptibility ge...

journal_title：Biological research

authors： Jara L,Ampuero S,Seccia L,Bustamante M,Blanco R,Ojeda JM

更新日期：2002-01-01 00:00:00

abstract：:Three innovative and complementary morphological approaches were employed to study the T cell/antigen presenting cell (APC) interaction: (i) high resolution three-dimensional confocal microscopy of the T cell-APC contact site; (ii) time lapse video recording in living T cells of [Ca2+]I and changes in distribution of ...

journal_title：Biological research

authors： Faroudi M,Zaru R,Favier B,Valitutti S

更新日期：2002-01-01 00:00:00

abstract：:Apoptosis is a means by which organisms dispose of unwanted cells without inducing an inflammatory response. Alterations in apoptosis is a common process by which cells become cancerous. Paradoxically, many cancer chemotherapeutics preferentially kill cancer cells by inducing apoptosis. Diacylglycerol is a lipid secon...

journal_title：Biological research

authors： Wright MM,McMaster CR

更新日期：2002-01-01 00:00:00

abstract：:Adenovirus genotype 7h was previously reported to be originated from a recombination event between adenovirus genotypes 7p and 3p. Based on those findings, further characterization of other adenovirus 7h strains become important to determine whether all adenovirus 7h strains arose from a single recombinational event. ...

journal_title：Biological research

authors： Bruzzone M,Barro M,Spencer E

更新日期：2001-01-01 00:00:00

abstract：:Tumor growth is the result of combined cell proliferation overwhelming cell death and neoangiogenesis. This report shows CAM angiogenesis promoted by TA3 tumor supernatant with or without low dosis of betamethasone (Minimal antiangiogenic concentration: beta-MAAC). Methylcellulose discs instilled with 10 microliters o...

journal_title：Biological research

authors： Lemus D,Dabancens A,Illanes J,Fuenzalida M,Guerrero A,López C

更新日期：2001-01-01 00:00:00

abstract：:Eight Chilean strains of Dunaliella salina obtained within a restricted geographic range, but exhibiting a high variability in their morphology, rate of growth and carotenogenic capacity, were analyzed by Random Amplified Polymorphic DNA (RAPD-PCR) Twenty of the 50 random primers (D, P, OPA and OPD series) that were t...

journal_title：Biological research

authors： Gomez PI,Gonzalez MA

更新日期：2001-01-01 00:00:00

abstract：:Cells tightly regulate iron levels through the activity of iron regulatory proteins (IRPs) that bind to RNA motifs called iron responsive elements (IREs). When cells become iron-depleted, IRPs bind to IREs present in the mRNAs of ferritin and the transferrin receptor, resulting in diminished translation of the ferriti...

journal_title：Biological research

authors： Nuñez MT,Garate MA,Arredondo M,Tapia V,Muñoz P

更新日期：2000-01-01 00:00:00

abstract：:Red blood cell carbonic anhydrase (CA) activity has not been studied in high altitude natives. Because CA is an intraerythocytic enzyme and high altitude natives are polycythemic, it is important to know if the activity of CA per red cell volume is different from that of their sea level counterparts. Blood was collect...

journal_title：Biological research

authors： Gamboa J,Caceda R,Gamboa A,Monge-C C

更新日期：2000-01-01 00:00:00

abstract：:The development of plant transformation in the mid-1980s and of many new tools for cell biology, molecular genetics, and biochemistry has resulted in enormous progress in plant biology in the past decade. With the completion of the genome sequence of Arabidopsis thaliana just around the corner, we can expect even fast...

journal_title：Biological research

authors： Chrispeels MJ,Holuigue L,Latorre R,Luan S,Orellana A,Peña-Cortes H,Raikhel NV,Ronald PC,Trewavas A

更新日期：1999-01-01 00:00:00

abstract：:Vasopressin and bradykinin are two of the most important peptides in regulating vascular tone, water, and ionic balance in the body, and thus they play a key role in controlling blood pressure. In addition to being a potent vasoconstrictor, Vasopressin also has an antidiuretic activity in the kidney, whereas kinins re...

journal_title：Biological research

authors： Gonzalez CB,Figueroa CD

更新日期：1999-01-01 00:00:00

abstract：:Santiago de Chile has a high level of air pollution with ozone (O3), carbon monoxide (CO) and particles equal or smaller than 10 microns (PM10) usually exceeding the accepted standards. This situation should be noxious for the exposed population and particularly--in the case of O3 and PM10--for the respiratory system....

journal_title：Biological research

authors： Oyarzún M,Pino P,Ortiz J,Olaeta I

更新日期：1998-01-01 00:00:00

abstract：:Studies of kallikrein-kinin systems since the 1930's have now led to substantial insight into the importance of this vasoactive system in the regulation of cardiovascular and renal function. It now seems clear that before long, these insights will lead to new therapeutic attacks upon diseases of the cardiovascular sys...

journal_title：Biological research

authors： Margolius HS

更新日期：1998-01-01 00:00:00

abstract：:Angiotensin-(1-7) [Ang-(1-7)] possesses novel biological functions that are distinct from angiotensin II (Ang II). In coronary arteries, the octapeptide Ang II and the heptapeptide Ang-(1-7) exert opposing actions. Ang II elicits vasoconstriction and Ang-(1-7) is a vasodilator. Ang-(1-7) elicits vasodilation by an end...

journal_title：Biological research

authors： Brosnihan KB,Li P,Tallant EA,Ferrario CM

更新日期：1998-01-01 00:00:00

abstract：:Prolactin (PRL) is a pituitary hormone that plays important roles in mammalian reproductive physiology, specially lactation. The regulation of PRL secretion shows important species differences. To study PRL regulation in a subhuman primate, the Cebus apella, we developed an heterologous radioimmunoassay using an antib...

journal_title：Biological research

authors： Vásquez K,Vergara M,Recabarren M,Brandeis A,Serón-Ferré M

更新日期：1997-01-01 00:00:00

abstract：:Galectins (S-type or S-Lac lectins) are a well-defined family of beta-galactoside animal lectins characterized by a high sequence homology in the carbohydrate-binding domain. We have previously purified and characterized the S-type lectin from the ovary of the toad Bufo arenarum. In this study, we purified the S-type ...

journal_title：Biological research

authors： Elola MT,Fink NE

更新日期：1997-01-01 00:00:00

abstract：:Most Colombian populations stem from the admixture of Caucasians, Amerindians and Negroids. In the world, these two latter ethnical groups show a significantly higher prevalence of epilepsy than the former one. We tested the hypothesis that the high prevalence of idiopathic epilepsy with generalized tonic clonic seizu...

journal_title：Biological research

authors： Jiménez I,Mora O,Lopez G,Jiménez ME,Zuluga L,Isaza R,Sanchez JL,Uribe CS,Valenzuela CY,Blanco R,Arcos-Burgos M

更新日期：1996-01-01 00:00:00

abstract：:Bilateral aspiration lesions of the fimbria-fornix were performed in 10 male Sprague Dawley rats weighing 240-300 g under chloral hydrate narcose (420 mg/kg). Another 9 animals were operated in the same way, but no aspiration was carried out to constitute a control group. A week after surgery recording and stimulation...

journal_title：Biological research

authors： Bergado JA,Moreno H,Nuñez N

更新日期：1996-01-01 00:00:00

abstract：:X-Ray diffraction is the only method currently available for the determination of the detailed three-dimensional structure of macromolecules. In this article, the principles behind the use of X-ray crystallography in the study of protein structure are presented. The results obtained in its application to several enzym...

journal_title：Biological research

authors： Cid H

更新日期：1996-01-01 00:00:00

abstract：:Invasive properties of 15 strains of thermotolerant Campylobacter (12 C. jejuni and 3 C. coli) were studied using HeLa cells cultures. In four of them (3 C. jejuni and 1 C. coli), randomly selected, intestinal perfusion experiments were conducted in order to asses enterotoxigenicity. All strains were able to invade He...

journal_title：Biological research

authors： Fernández H,Trabulsi LR

更新日期：1995-01-01 00:00:00

abstract：:Transducin serves as a mediator between the receptor protein, rhodopsin, and the effector protein, cGMP phosphodiesterase, in the visual process. Transducin is a protein composed of three polypeptides: T alpha, T beta, and T gamma, and acts as two functional units, the alpha-subunit and the beta gamma-complex. In the ...

journal_title：Biological research

authors： Bubis J

更新日期：1995-01-01 00:00:00

abstract：:Unilateral brain damage which includes the hippocampus leads to memory impairments consistent with hemispheric specialization on the same side. Damage to the corpus callosum, the major connecting pathway between the left and right hemispheres, also leads to memory impairments. This suggests both hemispheric specializa...

journal_title：Biological research

authors： Zaidel DW

更新日期：1995-01-01 00:00:00

abstract：:Bovine median eminence contains a factor difference from gonadotropin-releasing hormone (GnRH) than increases basal luteinizing hormone (LH) secretion and potentiates GnRH-stimulated LH release. We compared the effect of hypothalamic neuropeptides on basal and GnRH-stimulated LH secretion using rat pituitary cells und...

journal_title：Biological research

authors： Leiva LA,Croxatto HB

更新日期：1994-01-01 00:00:00

abstract：:The present work was intended to evaluate the preparation of antigens, as well as the production and characterization of anti cAMP and cGMP antibodies. Such antibodies were obtained from rabbits, and we used 2'O-succinyl cyclic nucleotide derivate, conjugated with human serum albumin, as antigen. The characterization ...

journal_title：Biological research

authors： Defagot C,Zubin P

更新日期：1994-01-01 00:00:00

abstract：:Renal response to atrial natriuretic peptide in chronic cholestasis was studied in anaesthetized rats and in their isolated perfused kidneys. Cholestasis was induced by bile duct section after ligature, while controls were sham operated. Three weeks after surgery, cholestatic rats showed moderate arterial hypotension,...

journal_title：Biological research

authors： Valdivieso A,Boric MP,Riquelme A,Roblero J

更新日期：1993-01-01 00:00:00

abstract：:The major cysteine proteinase from Trypanosoma cruzi, cruzipain, can be obtained essentially homogeneous, starting from crude epimastigote extracts, in one step, by affinity chromatography on Cystatin-Sepharose (specific for cysteine proteinases) or ConA-Sepharose (specific for high mannose N-linked glycoproteins). Th...

journal_title：Biological research

authors： Labriola C,Sousa M,Cazzulo JJ

更新日期：1993-01-01 00:00:00

abstract：:Guanine nucleotide binding proteins (GTP-binding proteins) function as transducers of signals in different cellular processes. We have identified several GTP-binding proteins in Trypanosoma cruzi by Western blot analyses. Six polypeptide bands, p20, p25, p28, p31, p37 and p38, were specifically detected in epimastigot...

journal_title：Biological research

authors： Bubis J,Millan EJ,Martinez R

更新日期：1993-01-01 00:00:00